The H&R Block tax software is very easy to use and even easier to file with. Refunds by direct deposit seem to come through very quickly, just a few weeks. Last year when I had to pay, it came out of my account within days. I feel confident in my returns when I use Block.
This software evolved from TaxCut by MECA, which was my first tax software, so I feel at home with it. So far, both the IRS and the State equivalent have accepted the results. Doesn't work quite as well with Quicken as I would like.