Anything you can do now on your cable box remote can be programmed.
I have my Sony TV, Comcast DVR, Roku Ultra, Blu-Ray player, Apple TV and programmed and have 100% of the features (including a 30 sec skip for commercials on DVR)
It takes time, but if you program it correctly you do not lose anything. I also check next day forward and back on program guide and also scheduled recordings