It really depends on the case. I have a Spigen rugged armor but I haven't put mine on yet as I just had my SP installed about 3 hrs ago. I'm going to wait 48 hrs as suggested, however, the young lady at BB that installed mine had this protector on hers with a Spigen liquid crystal case on hers and it looked great! I even took her case off to look at the rounded curves and edges and it was laying flat all around. Color me convinced!