Live-action comedy and exciting animated adventure come together for a wild ride through the human anatomy in the outrageous Osmosis Jones. Warner has done an excellent job on this disc beginning with a very well-rendered 2.35:1 anamorphic widescreen transfer. All aspects of this disc, including color patterns, fleshtones, and black levels, look very even and natural. No imperfections or edge enhancement are spotted anywhere during the film. Audio is presented in Dolby Digital 5.1 Surround in English and French, as well as Dolby Digital 2.0 in Spanish. The 5.1 soundtrack utilizes surround effects generously throughout the film. Bodily sounds such as gastric juices and flowing snot surround the viewer during the entire film. Also included on this disc are English and French subtitles. Osmosis Jones is filled to the brim with some icky special features, starting off with a commentary track by animation directors Piet Kroon and Tom Sito, writer Marc Hyman, and producer Zak Penn. This is a very chatty audio track that gives much information about the production and design of the film. Two documentaries ("HBO First Look Special" and "Investigating the Vocal Chords") provide a detailed look into the voice-over talent needed for the film, as well as interviews with some of the cast and crew. Finally there are a few unfinished "deleted scenes," a theatrical trailer for the film, and a section titled "Frank's Anatomy" that allows the viewer to jump to certain scenes (located in certain parts of the body). Fans of the gross and weird should have a ball with this edition of Osmosis Jones.