As you look down over the bustling, lively city of Manhattan, your mind whirs with the commotion of flashing lights and loudly blaring noises — your spidey senses begin to tingle. Crime lurks in every darkened alley and shadows threaten to overtake the light. In one deft move, you leap confidently from your spot perched atop a skyscraper and begin a dazzling sequence of acrobatic maneuvers, web-slinging your way across a city that you have deemed your personally protected playground. In this exciting story placed alongside the events of the second film, The Amazing Spider-Man 2 lets you continue the adventures of Peter Parker as you search relentlessly for the person — or creature — who murdered your Uncle Ben.Put on the suit and slip on the mask of everyone's favorite neighborhood Spider-Man in this all-new adventure. Investigate and overpower a creative cast of all-star convicts and stop crime dead in its tracks. Explore the streets and skyline of New York City as you use your expansive web-slinging mechanics to glide over the cityscape on trusty strands of web. Perform a series of signature acrobatic combat moves to bring your enemies to their knees and keep evil at bay. Receive rewards for fighting crime or face the punishments if you fail to do so with the new Hero or Menace system. Take advantage of your expanded web-shooting capabilities to take down foes and unleash powerful chemical properties to freeze and blow up items on impact. Step out of the limelight and return to Spider-Man's citizen alter ego, Peter Parker, in order to hunt down the motivations of Manhattan's maniacal masterminds. Are you ready for an action-packed, adrenaline-pumping adventure with everyone's favorite web slinger?

Team leader Susan joins Link, Dr. Cockroach, and the gelatinous blob known as B.O.B find one adventure after the next while residing in an ultra-secret government containment area run by General Monger.