Desperate to rid the Miramar Playa Hotel of Ben Diamond (Danny Huston), proprietor Ike Evans (Jeffrey Dean Morgan) attracts the attention of a Chicago crime boss (James Caan). Elsewhere, Ike's relationship with his two sons continues to deteriorate.

The sitcom's 11th season is the first without Angus T. Jones as Jake, but the Harper gene pool is a deep one as Amber Tamblyn joins the cast as Jenny, Charlie's long-lost, out-of-wedlock daughter who shares her late father's love for alcohol--and women. An aspiring actor, Jenny quickly bonds with Walden (Ashton Kutcher) and her uncle, Alan (Jon Cryer), and eventually moves into the beach house. In other developments, Alan and Lyndsey (Courtney Thorne-Smith) embark on a sex-only relationship until she starts dating Larry (D.B. Sweeney) and Alan falls for Larry's sister, Gretchen (Kimberly Williams-Paisley); Walden helps a former employee (Odette Annable) with her software start-up; Berta (Conchata Ferrell) mulls retirement; and Evelyn (Holland Taylor) gets ready to tie the knot with Marty (Carl Reiner).

Season 4 of the Prohibition-era drama opens in February 1924 as Nucky (Steve Buscemi) makes peace with New Yorkers Masseria (Ivo Nandi) and Rothstein (Michael Stuhlbarg), moves into the abandoned Albatross Hotel and, coincidentally, spreads his wings with a potential real-estate bonanza in Florida, where he's smitten with a saucy barkeep (Patricia Arquette). Back in Atlantic City, Chalky (Michael K. Williams) runs the boardwalk's Onyx Club, though the mysterious Harlem intellectual Dr. Narcisse (Jeffrey Wright) challenges his North Side reign, and Eddie (Anthony Laciura) finally gets a promotion. In Philadelphia, Eli's son Willie (Ben Rosenfield) dives in over his head at college; while in the Midwest, Nelson (Michael Shannon) pulls double duty for Chicago mobsters Capone (Stephen Graham) and O'Banion (Arron Shiver), and a wandering Richard (Jack Huston) reconnects with his roots. With Shea Whigham, Brian Geraghty, Ron Livingston, Margot Bingham, Anatol Yusef and Domenick Lombardozzi.