The 10th season of this medical drama finds the doctors trying to care for storm victims, and among the victims is an electrocuted Webber (James Pickens Jr.), who has put Meredith (Ellen Pompeo) in charge of his medical decisions. The hospital itself is damaged in the storm, which results in Owen (Kevin McKidd) and Jackson (Jesse Williams) clashing over finance issues. But they're not the only ones fighting: Callie (Sara Ramirez) and Arizona (Jessica Capshaw) struggle to reconcile in the wake of Arizona's infidelity; and best friends Meredith and Cristina (Sandra Oh) have a falling-out over a work matter. Meanwhile, Meredith also has trouble balancing work and motherhood after she and Derek (Patrick Dempsey) return to work following the birth of their son; and Alex (Justin Chambers) sees his estranged father, who's a drug addict, arrive in the ER as a patient.

The second season of this sci-fi thriller continues to follow orphan Sarah Manning (Tatiana Maslany) throughout a deadly conspiracy after learning that she is not only a clone, but that there are others out there like her - some of whom don't have the best intentions.