Yes, I have a Roku and amazon fire TV stick and have tried both.once you to to the input the tv remote runs the Roku or Fire Stick and when I got to my PS4 Pro input it turns on the PS4 and I have basic navigation through the TV remote. Also the voice remote works very well, just push the button say Roku and it goes to that input and if you're watching Roku and you want to switch to TV (I am a cord cutter with an antenna) you just tell it to got to channel # and it changes, then push the button and say PlayStation and it changes to that and turns on the PS4 or say settings and go to settings, Say Netflix and it to the the TVs Netflix app. the TV and remote are both Awesome!