The answer is yes, but it depends on your model of computer/laptop.
I have 3 monitors connected to my Dell Latitude 5400 laptop (with i7 Processor and 16GB RAM). It does depend on the model/year as my previous Dell laptop did not have the USB C display port (aka USB 3.1 Gen 2) and could barely extend to two monitors and keep the laptop screen on. Now I have use of the 3 monitors and the laptop screen. I have not t tried a 4th. I don't think my laptop would support that many anyways.