This collection includes all 12 episodes from the first season of the HBO western series Deadwood, created by David Milch and set in 1876 South Dakota. The story largely centers around new Deadwood resident and hardware shop owner Seth Bullock (Timothy Olyphant) and Al Swearengen (Ian McShane), the foul-mothed owner of local sallon and brothel The Gem. Deadwood mixes characters who prominently figure into American history, including Wild Bill Hickok (Keith Carradine) and Calamity Jane (Robin Weigert), with fictionalized amalgamations of other figures from the time, such as Alma Garret (Molly Parker) and Doc Cochran (Brad Dourif).

All ten episodes of the award-winning medical drama series' second season, set in 1901, is available in this collection. Dr. John Thackery (Clive Owen) continues to perform cutting-edge operations, including an electrical brain stimulation and a devised procedure to seperate conjoined twins, all while battling a heroin addiction that is becoming increasingly dire. Meanwhile, the gifted Dr. Algernon Edwards (Andre Holland), who has ascended to the role of acting chief of surgery, continues to face racially-charged disrespect while dealing with the reappearance of his strong-willed wife, Opal (Zaraah Abrahams). Subplots include Nurse Elkins' (Eve Hewson) search for personal and professional fulfillment, a fiery, near-death experience and various other events in and out of Knickerbocker Hospital with grave consequences. All ten episodes are directed by Academy Award-winning director Steven Soderbergh.